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Article

A dichotomy in association of core transcription factors and gene regulation during the activated B-cell to plasmablast transition

2019-12-23

Abstract excerpt

The activated B-cell (ABC) to plasmablast transition is the cusp of antibody secreting cell (ASC) differentiation but is incompletely defined. We apply expression time-courses, parsimonious gene correlation network analysis, and ChIP-seq to explore this in human cells. The transition initiates with input signal loss leading within hours from cell growth dominant programs to enhanced proliferation, accompanied from...

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Literature Corpus work
155305bd-04c7-5c8c-879c-76de307f21b0
DOI
10.1101/2019.12.23.884007
Open publication

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A dichotomy in association of core transcription factors and gene regulation during the activated B-cell to plasmablast transitionDOI 10.1101/2019.12.23.884007
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