Article

Integrated single-cell (phospho-)protein and RNA detection uncovers phenotypic characteristics of human antibody secreting cells

2022-04-01

Abstract excerpt

Antibody-secreting cells (ASCs) secrete IgM, IgA, or IgG antibodies and are key components of humoral immunity; however, little is known about unique characteristics of the Ig-classes due to limited availability of material and challenges to quantify many intracellular molecular modalities at a single-cell resolution. We combined a method to in vitro differentiate peripheral B-cells into ASCs with integrated multi...

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Literature Corpus work: 95e42737-2935-5d5f-bf3a-18f28ad0e814
DOI: 10.1101/2022.03.31.486501

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