Article

ChromaFold predicts the 3D contact map from single-cell chromatin accessibility

2023-07-28

Abstract excerpt

The identification of cell-type-specific 3D chromatin interactions between regulatory elements can help to decipher gene regulation and to interpret the function of disease-associated non-coding variants. However, current chromosome conformation capture (3C) technologies are unable to resolve interactions at this resolution when only small numbers of cells are available as input. We therefore present ChromaFold, a...

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Literature Corpus work: ce2f6578-d5f7-53c5-bce5-2ac6ae0b4099
DOI: 10.1101/2023.07.27.550836

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