Article

Hi-Compass resolves cell-type chromatin interactions by single-cell and spatial ATAC-seq data across biological scales

2025-05-17

Abstract excerpt

Computational prediction of three-dimensional (3D) genome organization provides an alternative approach to overcome the cost and technical limitations of Hi-C experiments. However, current Hi-C prediction models are constrained by their narrow applicability to studying the impact of genetic variation on genome folding in specific cell lines, significantly restricting their biological utility. We present Hi-Compass...

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Literature Corpus work: 53262c4c-6b99-5692-a1e5-75355218c987
DOI: 10.1101/2025.05.14.654019

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