Article

Revealing the transcription factor regulatory context of human specific cortical development using single-cell multi-omics

2021-03-19

Abstract excerpt

Human behaviors are at least partially driven by genomic regions that influence human-specific neurodevelopment. This includes genomic regions undergoing human specific sequence acceleration (Human Accelerated Regions or HARs) and regions showing human-specific enhancer activity (Human Gained Enhancers or HGEs) not present in other primates. However, prior studies on HAR/HGE activities involved mixtures of brain c...

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Literature Corpus work: 12ed834f-cd5a-5bdb-a696-78f645f1a732
DOI: 10.1101/2021.03.19.436193

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