Article

Dissecting regulatory syntax in human development with scalable multiomics and deep learning

2025-04-30

Abstract excerpt

Transcription factors (TFs) establish cell identity during development by binding regulatory DNA in a sequence-specific manner, often promoting local chromatin accessibility, and regulating gene expression. Mapping accessible chromatin offers critical insights into transcriptional control, but available datasets for human development are restricted to bulk tissue, single organs, or single modalities. Here, we pres...

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Literature Corpus work: 600a07c2-2163-5323-96d6-9d61535cd7f5
DOI: 10.1101/2025.04.30.651381

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