Article

Cell-type specific effects of genetic variation on chromatin accessibility during human neuronal differentiation

2020-01-14

Abstract excerpt

<h4>Summary</h4> Common genetic risk for neuropsychiatric disorders is enriched in regulatory elements active during cortical neurogenesis. However, the mechanisms mediating the effects of genetic variants on gene regulation are poorly understood. To determine the functional impact of common genetic variation on the non-coding genome longitudinally during human cortical development, we performed a chromatin acces...

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Literature Corpus work: 7d2793d3-e217-59a3-8c6c-531e40107beb
DOI: 10.1101/2020.01.13.904862

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