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Article

A single-cell atlas of chromatin accessibility in the human genome.

Cell - 24 Nov 2021

Zhang Kai, Hocker James D, Miller Michael, Hou Xiaomeng, Chiou Joshua, Poirion Olivier B, Qiu Yunjiang, Li Yang E, Gaulton Kyle J, Wang Allen, Preissl Sebastian, Ren Bing

Abstract excerpt

Current catalogs of regulatory sequences in the human genome are still incomplete and lack cell type resolution. To profile the activity of gene regulatory elements in diverse cell types and tissues in the human body, we applied single-cell chromatin accessibility assays to 30 adult human tissue types from multiple donors. We integrated these datasets with previous single-cell chromatin accessibility data from 15...

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Identifiers

PMID: 34774128
DOI: 10.1016/j.cell.2021.10.024
PMCID: PMC8664161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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