Article
Genomic copy number predicts oesophageal cancer years before transformation
2020-02-28
Abstract excerpt
<h4>Summary</h4> Cancer arises through a process of somatic evolution and recent studies have shown that aneuploidies and driver gene mutations precede cancer diagnosis by several years to decades 1–4 Here, we address the question whether such genomic signals can be used for early detection and pre-emptive cancer treatment. To this end we study Barrett’s oesophagus, a genomic copy number driven neoplastic precur...
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Identifiers and source
- Literature Corpus work
- 0f801342-b587-5b28-8a44-6713cf9f7f4b
- DOI
- 10.1101/2020.02.27.967612