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Article

Genetic progression of Barrett's oesophagus to oesophageal adenocarcinoma.

British journal of cancer - 9 Aug 2016

Gregson Eleanor M, Bornschein Jan, Fitzgerald Rebecca C

Abstract excerpt

Barrett's oesophagus (BE) is the premalignant condition associated with the development of oesophageal adenocarcinoma (OAC). Diagnostically, p53 immunohistochemistry remains the only biomarker recommended clinically to aid histopathological diagnosis. The emerging mutational profile of BE is one of highly heterogeneous lesions at the genomic level with many mutations already occurring in non-dysplastic tissue. As...

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Identifiers

PMID: 27441494
DOI: 10.1038/bjc.2016.219
PMCID: PMC4985359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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