Article

( <i>2R,6R</i> )-hydroxynorketamine facilitates extinction and prevents emotional impairment and stress-induced reinstatement in morphine abstinent mice

2023-12-08

Abstract excerpt

<h4>ABSTRACT</h4> Opioid addiction is a pressing public health concern marked by frequent relapse during periods of abstinence, perpetuated by negative affective states and anhedonia-driven behaviors. In addition to the current epidemic that was declared in the U.S.A., opioid-related deaths are increasing in other countries around the world. Classical antidepressants, or the currently prescribed opioid substituti...

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Literature Corpus work: 0d4a7677-19bf-5691-ada6-7dcbeeb31d85
DOI: 10.1101/2023.12.07.570550

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