Article

Cross-reactivity reduced dengue virus serotype 2 vaccine does not confer cross-protection against other serotypes of dengue viruses

2018-11-27

Abstract excerpt

The four serotypes of dengue virus (DENV) cause the most important rapidly emerging arthropod-borne disease globally. The humoral immune response to DENV infection is predominantly directed against the immunodominant cross-reactive weakly neutralizing epitopes located in the highly conserved fusion peptide of ectodomain II of envelope (E) protein (EDII FP ). Antibodies recognizing EDII FP have been shown to asso...

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Literature Corpus work: 0d2ffef1-4468-581a-bc93-015032d408b3
DOI: 10.1101/480210

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