Article

COVID-19 Vaccination Induces Cross-Reactive Dengue Antibodies with Altered Isotype Profiles and In Vitro ADE

2025-05-25

Abstract excerpt

Dengue virus is a mosquito transmitted flavivirus that cause inapparent or mild disease but can also cause severe hemorrhagic fever in humans. Cross-reactive IgG antibodies can cause under specific conditions antibody dependent enhancement (ADE) of the infection via Fc-receptor interaction. Antibodies from SARS-CoV-2 (anti-S) causing COVID-19 disease can also cross-react against the dengue envelope (anti-E). We th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 279d8fc6-c81a-57e0-8ab1-7357efd5ec03
DOI: 10.1101/2025.05.23.25328123

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

COVID-19 Vaccination Induces Cross-Reactive Dengue Antibodies with Altered Isotype Profiles and In Vitro ADEDOI 10.1101/2025.05.23.25328123Read

Immunopathogenesis of dengue haemorrhagic feverSemantic proximity Read

Generation and therapeutic efficacy of the novel Fc-modified cross-neutralizing human monoclonal antibodies against dengue virusSemantic proximity Read

Cross-reactivity reduced dengue virus serotype 2 vaccine does not confer cross-protection against other serotypes of dengue virusesSemantic proximity Read

Antibody germline characterization of cross-neutralizing human IgGs against 4 serotypes of dengue virusSemantic proximity Read

Humoral Response to Dengue Virus Infections Potentiates Antibody-Dependent Enhancement of SARS-CoV-2Semantic proximity Read

Humoral Immune Responses in Patients with Severe COVID-19: A Comparative Study between Individuals Infected by SARS-CoV-2 during the Wild-Type and the Delta PeriodsSemantic proximity Read

Autoimmunity and Antibody Dependent COVID-19 Enhancement of SARS CoV-2 Vaccination: A Global Human Right to Know then Decide.Semantic proximity Read

Dengue Virus Antibodies Enhance Zika Virus InfectionSemantic proximity Read

Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention.Semantic proximity Read

Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein.Semantic proximity Read

Antibody with an engineered Fc region as a therapeutic agent against dengue virus infection.Semantic proximity Read

Differential Protein Expression in Dengue Patients with SARS-CoV-2 IgG Antibodies: Implications of Disease Severity and Antibody Dependent EnhancementSemantic proximity Read