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Article

Protective Role of Cross-Reactive CD8 T Cells Against Dengue Virus Infection.

EBioMedicine - 1 Nov 2016

Elong Ngono Annie, Chen Hui-Wen, Tang William W, Joo Yunichel, King Kevin, Weiskopf Daniela, Sidney John, Sette Alessandro, Shresta Sujan

Abstract excerpt

Infection with one of the four dengue virus serotypes (DENV1-4) presumably leads to lifelong immunity against the infecting serotype but not against heterotypic reinfection, resulting in a greater risk of developing Dengue Hemorrhagic Fever/Dengue Shock Syndrome (DHF/DSS) during secondary infection. Both antibodies and T cell responses have been implicated in DHF/DSS pathogenesis. According to the T cell-based...

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Source

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Identifiers

PMID: 27746192
DOI: 10.1016/j.ebiom.2016.10.006
PMCID: PMC5264312

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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