Article

Chromatin accessibility dynamics of myogenesis at single cell resolution

2017-06-26

Abstract excerpt

Over a million DNA regulatory elements have been cataloged in the human genome, but linking these elements to the genes that they regulate remains challenging. We introduce Cicero, a statistical method that connects regulatory elements to target genes using single cell chromatin accessibility data. We apply Cicero to investigate how thousands of dynamically accessible elements orchestrate gene regulation in differ...

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Literature Corpus work: 0b87ac86-1595-5c38-b092-8b22bedebfef
DOI: 10.1101/155473

Open publication

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