Article

Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneity

2018-05-19

Abstract excerpt

Integrative analysis of multi-omics layers at single cell level is critical for accurate dissection of cell-to-cell variation within certain cell populations. Here we report scCAT-seq, a technique for simultaneously assaying chromatin accessibility and the transcriptome within the same single cell. We show that the combined single cell signatures enable accurate construction of regulatory relationships between ci...

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Literature Corpus work: e254d3c8-4846-546f-ae01-b718b91200a7
DOI: 10.1101/316208

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