Article

SCENIC+: single-cell multiomic inference of enhancers and gene regulatory networks

2022-08-19

Abstract excerpt

Joint profiling of chromatin accessibility and gene expression of individual cells provides an opportunity to decipher enhancer-driven gene regulatory networks (eGRN). Here we present a new method for the inference of eGRNs, called SCENIC+. SCENIC+ predicts genomic enhancers along with candidate upstream transcription factors (TF) and links these enhancers to candidate target genes. Specific TFs for each cell type...

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Literature Corpus work: c5b957f1-8e0e-5226-922a-2d53e2b89cfa
DOI: 10.1101/2022.08.19.504505

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