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Article

Cis-regulatory determinants of MyoD function.

Nucleic acids research - 21 Aug 2018

Soleimani Vahab D, Nguyen Duy, Ramachandran Parameswaran, Palidwor Gareth A, Porter Christopher J, Yin Hang, Perkins Theodore J, Rudnicki Michael A

Abstract excerpt

Muscle-specific transcription factor MyoD orchestrates the myogenic gene expression program by binding to short DNA motifs called E-boxes within myogenic cis-regulatory elements (CREs). Genome-wide analyses of MyoD cistrome by chromatin immnunoprecipitation sequencing shows that MyoD-bound CREs contain multiple E-boxes of various sequences. However, how E-box numbers, sequences and their spatial arrangement...

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Identifiers

PMID: 30016497
DOI: 10.1093/nar/gky388
PMCID: PMC6101602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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