Article

A genome-wide, machine learning-guided exploration of the cis-regulatory code involved in neuronal differentiation

2025-05-15

Abstract excerpt

Gene expression is controlled by proximal and distal cis-regulatory elements (CREs), containing DNA motifs bound by various transcription factors (TFs). Other sequence features, such as specific k-mers or low complexity regions, have also been implicated. However, in a dynamic biological process such as cell differentiation, we lack an understanding of how the transcriptional activity of CREs progressively change...

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Literature Corpus work: 648131a3-5eda-5e3b-b340-3edec20b50ab
DOI: 10.1101/2025.05.14.653995

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