Article

Identification of DNA motifs that regulate DNA methylation

2019-03-11

Abstract excerpt

DNA methylation is an important epigenetic mark but how its locus-specificity is decided in relation to DNA sequence is not fully understood. Here, we have analyzed 34 diverse whole-genome bisulfite sequencing datasets in human and identified 313 motifs, including 92 and 221 associated with methylation (methylation motifs, MMs) and unmethylation (unmethylation motifs, UMs), respectively. The functionality of these...

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Literature Corpus work: 09940ca1-98c3-5447-9335-59696bd542cf
DOI: 10.1101/573352

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