Article
DNA methylation and DNA methyltransferases.
Epigenetics & chromatin - 1 Jan 2017
Edwards John R, Yarychkivska Olya, Boulard Mathieu, Bestor Timothy H
Abstract excerpt
The prevailing views as to the form, function, and regulation of genomic methylation patterns have their origin many years in the past, at a time when the structure of the mammalian genome was only dimly perceived, when the number of protein-encoding mammalian genes was believed to be at least five times greater than the actual number, and when it was not understood that only ~10% of the genome is under selective...
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