Article

CanASM: A comprehensive database for genome-wide allele-specific DNA methylation identification and annotation in cancer

2025-04-08

Abstract excerpt

Allele-specific DNA methylation (ASM) provides critical insights into the complex genetic and epigenetic mechanisms regulating gene transcription. Emerging evidence suggests that ASM is particularly enriched in gene enhancer regions, and recent studies have demonstrated that ASM is increased in cancer tissues compared with normal tissues. Despite the increasing recognition of ASM as a potential biomarker in tumori...

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Literature Corpus work: 3ae7eaf3-f510-54f3-bad1-dd7062be53b2
DOI: 10.1101/2025.04.03.646980

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