Article
Genome-wide distribution of DNA methylation at single-nucleotide resolution.
Progress in molecular biology and translational science - 1 Jan 2011
Wong Eleanor, Wei Chia-Lin
Abstract excerpt
DNA methylation, a well-known epigenetic modification in mammalian genomes, is important for development and health. Dysregulation of DNA methylation can cause abnormal gene regulation, leading to anomalous development and diseases. Until recently, the ability to understand the functions and dynamics of DNA methylation was limited by the availability of technologies for comprehensively characterizing methylation...
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