Article
Mapping of Variable DNA Methylation Across Multiple Cell Types Defines a Dynamic Regulatory Landscape of the Human Genome.
G3 (Bethesda, Md.) - 7 Apr 2016
Gu Junchen, Stevens Michael, Xing Xiaoyun, Li Daofeng, Zhang Bo, Payton Jacqueline E, Oltz Eugene M, Jarvis James N, Jiang Kaiyu, Cicero Theodore, Costello Joseph F, Wang Ting
Abstract excerpt
DNA methylation is an important epigenetic modification involved in many biological processes and diseases. Many studies have mapped DNA methylation changes associated with embryogenesis, cell differentiation, and cancer at a genome-wide scale. Our understanding of genome-wide DNA methylation changes in a developmental or disease-related context has been steadily growing. However, the investigation of which CpGs...
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