Article
New insights on the role of DNA methylation from a global view.
Frontiers in bioscience (Landmark edition) - 1 Jan 2017
Meier Karin, Recillas-Targa Félix
Abstract excerpt
In mammals, DNA methylation is a crucial epigenetic modification with key functions during development. Cellular processes that are regulated by DNA methylation comprise X chromosome inactivation, gene imprinting, genomic stability and transcriptional regulation. Generally, the methylation status of the majority of target sites is reliably propagated during mitosis. However, advances in genome-wide DNA...
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