Article

Using polygenic risk scores for prioritising individuals at greatest need of a CVD risk assessment

2022-10-22

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> To provide quantitative evidence of the use of polygenic risk scores (PRS) for systematically identifying individuals for invitation for full formal cardiovascular disease (CVD) risk assessment. <h4>Methods</h4> 108,685 participants aged 40-69, with measured biomarkers, linked primary care records and genetic data in UK Biobank were used for model derivation and population hea...

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Literature Corpus work: 0888ba26-acda-5844-b15e-a14ebd2d219a
DOI: 10.1101/2022.10.20.22281120

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