Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polygenic Risk Scores to Identify CVD Risk and Tailor Therapy: Hope or Hype?

Current atherosclerosis reports - 28 Jun 2021

German Charles A, Shapiro Michael D

Abstract excerpt

PURPOSE OF REVIEW: The purpose of this review is to understand the conceptual basis and implications of polygenic risk scores (PRS) in assessing risk of future coronary artery disease (CAD). RECENT FINDINGS: Genetic information from the USA and beyond has been pooled together to create population-based biobanks, composed of millions of genotyped individuals, which have helped further our understanding of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronary Artery Disease
Share to Genetic Predisposition to Disease
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multifactorial Inheritance

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Identifiers

PMID: 34181090
DOI: 10.1007/s11883-021-00950-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polygenic Risk Scores to Identify CVD Risk and Tailor Therapy: Hope or Hype?PMID 34181090Read ↗

Clinical utility and implementation of polygenic risk scores for predicting cardiovascular disease: A clinical consensus statement of the ESC Council on Cardiovascular Genomics, the ESC Cardiovascular Risk Collaboration, and the European Association of Preventive CardiologySemantic proximity Read ↗

Polygenic risk scores in coronary artery disease.Semantic proximity Read ↗

Bridging traditional risk factors and genetic insights: A review on polygenic risk scores in cardiovascular diseasesSemantic proximity Read ↗

Polygenic Risk Scores: The Next Step for Improved Risk Stratification in Coronary Artery Disease?Semantic proximity Read ↗

Taking the next steps to implement polygenic risk scoring for improved risk stratification and primary prevention of coronary artery disease.Semantic proximity Read ↗

Polygenic Scores to Assess Atherosclerotic Cardiovascular Disease Risk: Clinical Perspectives and Basic Implications.Semantic proximity Read ↗

Clinical utility of polygenic risk scores for coronary artery disease.Semantic proximity Read ↗

The Role of Polygenic Risk Score in the General Population: Current Status and Future ProspectsSemantic proximity Read ↗

Advances and Applications of Polygenic Scores for Coronary Artery Disease.Semantic proximity Read ↗

Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease.Semantic proximity Read ↗

Polygenic Risk Score: Clinically Useful Tool for Prediction of Cardiovascular Disease and Benefit from Lipid-Lowering Therapy?Semantic proximity Read ↗

A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.