Article

Development and validation of a risk prediction algorithm for high-risk populations combining genetic and conventional risk factors of cardiovascular disease

2025-04-04

Abstract excerpt

<h4>Aim</h4> To develop a model for cardiovascular disease (CVD) risk, combining polygenic risk score (PRS) with traditional risk factors while assessing the added value of PRS in two cohorts of biobank participants. <h4>Methods</h4> Data of 128 209 participants from the Estonian Biobank recruited between 2003– 2011 and 2018–2019 without prevalent cardiovascular disease, was included. Hazard ratios (HR) for polyge...

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Literature Corpus work: c8247731-53b6-52cb-973e-83d695300037
DOI: 10.1101/2025.04.02.25324383

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