Article

Polygenic and clinical risk scores and their impact on age at onset of cardiometabolic diseases and common cancers

2019-08-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Polygenic risk scores (PRS) have shown promise in predicting susceptibility to common diseases. However, the extent to which PRS and clinical risk factors act jointly and identify high-risk individuals for early onset of disease is unknown. <h4>Methods</h4> We used large-scale biobank data (the FinnGen study; n=135,300), with up to 46 years of prospective follow-up, and the...

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Literature Corpus work: 48450b99-2e39-5f94-8ffd-1a2af1a9bb17
DOI: 10.1101/727057

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