Article
Polygenic Risk Score Implementation into Clinical Practice for Primary Prevention of Cardiometabolic Disease.
Genes - 9 Dec 2024
Hughes Julia, Shymka Mikayla, Ng Trevor, Phulka Jobanjit S, Safabakhsh Sina, Laksman Zachary
Abstract excerpt
Background: Cardiovascular disease is a leading cause of mortality globally and a major contributor to disability. Traditional risk factors, as initially established in the FRAMINGHAM study, have helped to stratify populations and identify patients for early intervention. Incorporating genetic factors enhances risk stratification tools, enabling the earlier identification of individuals at increased risk and...
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