Article

Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies

2017-08-02

Abstract excerpt

Our current understanding of cellular transdifferentiation systems is limited. It is oftentimes unknown, at a genome-wide scale, how much transdifferentiated cells differ quantitatively from both the starting cells and the target cells. Focusing on transdifferentiation of primary human skin fibroblasts by forced expression of myogenic transcription factor MyoD, we performed quantitative analyses of gene expression...

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Literature Corpus work: 0579d37f-1972-5a1d-9cdc-b3b37d318d27
DOI: 10.1101/171470

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