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Hypothesis-generating analysis of mutational signatures in childhood B-cell acute lymphoblastic leukemia in relation to socio-demographic, genetic, and environmental factors: A report from the Children’s Oncology Group

2025-10-09

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Signatures of mutational processes (mutSig) have the potential to fingerprint exposures present during tumor development. While several studies have described prevalence and burden of mutSig in pediatric populations, there have been few efforts to date to associate mutational signatures with exposures or lifestyle factors related to cancer risk. Studying relationships betwee...

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Literature Corpus work
044f50ad-7e34-5566-8bc5-44430972fb23
DOI
10.1101/2025.10.02.25336752
Open publication

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Hypothesis-generating analysis of mutational signatures in childhood B-cell acute lymphoblastic leukemia in relation to socio-demographic, genetic, and environmental factors: A report from the Children’s Oncology GroupDOI 10.1101/2025.10.02.25336752
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