Article
The Mutational Epidemiology of Childhood Cancer.
Clinical chemistry - 30 Dec 2025
Spector Logan G, Clark Cassandra, Lu Zhanni, Anderson Nathan, Marcotte Erin L, de Smith Adam James
Abstract excerpt
BACKGROUND: Childhood cancers comprise a variety of liquid and solid tumors that display different patterns of incidence than adult cancers. Most have distinct molecular subtypes characterized by specific genomic driver events. The mutational processes that influence the somatic landscape of cancers also generate distinctive mutational signatures (mutSig). While these signatures are often inert, they do represent...
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