Article
Investigating the causes of childhood acute lymphoblastic leukemia through mutational epidemiology.
Current problems in pediatric and adolescent health care - 1 Sept 2025
de Smith Adam J, Zhou Naying, Li Yunqi, Liu Tanxin, Patrus Nathan, Wiemels Joseph L
Abstract excerpt
Acute lymphoblastic leukemia (ALL) is the most common cancer in children, and prevention of this disease would significantly reduce childhood mortality and morbidity. While the role of germline genetic variation in the etiology of ALL is well established, the contribution of modifiable risk factors is less well known. Epidemiologic studies have identified several environmental and infectious or immune-related...
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