Article
Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.
Journal of the National Cancer Institute - 15 May 2013
Xu Heng, Yang Wenjian, Perez-Andreu Virginia, Devidas Meenakshi, Fan Yiping, Cheng Cheng, Pei Deqing, Scheet Paul, Burchard Esteban González, Eng Celeste, Huntsman Scott, Torgerson Dara G, Dean Michael, Winick Naomi J, Martin Paul L, Camitta Bruce M, Bowman W Paul, Willman Cheryl L, Carroll William L, Mullighan Charles G, Bhojwani Deepa, Hunger Stephen P, Pui Ching-Hon, Evans William E, Relling Mary V, Loh Mignon L, Yang Jun J
Abstract excerpt
BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common cancer in children and the incidence of ALL varies by ethnicity. Although accumulating evidence indicates inherited predisposition to ALL, the genetic basis of ALL susceptibility in diverse ancestry has not been comprehensively examined. METHODS: We performed a multiethnic genome-wide association study in 1605 children with ALL and 6661 control...
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