Article

Triple labeling resolves a GPCR intermediate state by 3-color single molecule FRET

2024-11-01

Abstract excerpt

The correlation of individual conformational changes in dynamic protein complexes remains challenging as most structural methods rely on averaged information over large numbers molecules. Single molecule FRET is a powerful tool for monitoring such conformational changes. When performed using three distinct probes, it enables the correlation of domain movements by providing up to three simultaneous distance measure...

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Identifiers and source

Literature Corpus work: 038b2cff-769e-51b8-abc1-5114b9533e9d
DOI: 10.1101/2024.10.31.621373

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