Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Brighter Red Fluorescent Proteins by Rational Design of Triple-Decker Motif.

ACS chemical biology - 19 Feb 2016

Pandelieva Antonia T, Baran Miranda J, Calderini Guido F, McCann Jenna L, Tremblay Véronique, Sarvan Sabina, Davey James A, Couture Jean-François, Chica Roberto A

Abstract excerpt

Red fluorescent proteins (RFPs) are used extensively in chemical biology research as fluorophores for live cell imaging, as partners in FRET pairs, and as signal transducers in biosensors. For all of these applications, brighter RFP variants are desired. Here, we used rational design to increase the quantum yield of monomeric RFPs in order to improve their brightness. We postulated that we could increase quantum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anthozoa
Share to Crystallography, X-Ray

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fluorescence

Share to Fluorescent Dyes

Share to Luminescent Proteins

Share to Models, Molecular

Share to Protein Conformation

Share to Red Fluorescent Protein

Source

Identifiers

PMID: 26697759
DOI: 10.1021/acschembio.5b00774

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Brighter Red Fluorescent Proteins by Rational Design of Triple-Decker Motif.PMID 26697759Read ↗

Structure-guided rational design of red fluorescent proteins: towards designer genetically-encoded fluorophores.Semantic proximity Read ↗

Generation of longer emission wavelength red fluorescent proteins using computationally designed libraries.Semantic proximity Read ↗

Influence of Fluorescence Lifetime Selections and Conformational Flexibility on Brightness of FusionRed Variants.Semantic proximity Read ↗

Improved Chemical-Genetic Fluorescent Markers for Live Cell Microscopy.Semantic proximity Read ↗

Mutagenesis of mNeptune Red-Shifts Emission Spectrum to 681-685 nm.Semantic proximity Read ↗

Conversion of red fluorescent protein into a bright blue probe.Semantic proximity Read ↗

Engineering a bright near-infrared fluorescent protein by screening a comprehensive phenotypic landscape.Semantic proximity Read ↗

Why a Single Mutation Dims the Light: Local Chromophore Organization Modulates Fluorescence in smURFP.Semantic proximity Read ↗

Structural origin and rational development of bright red noncanonical variants of green fluorescent protein.Semantic proximity Read ↗

Orange fluorescent proteins: structural studies of LSSmOrange, PSmOrange and PSmOrange2.Semantic proximity Read ↗

mRhubarb: Engineering of monomeric, red-shifted, and brighter variants of iRFP using structure-guided multi-site mutagenesis.Semantic proximity Read ↗

Rational design of photoconvertible and biphotochromic fluorescent proteins for advanced microscopy applications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.