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Article

Integrated structural modeling and super-resolution imaging resolve GPCR oligomers.

Progress in molecular biology and translational science - 1 Jan 2020

Fanelli Francesca, Hanyaloglu Aylin C, Jonas Kim

Abstract excerpt

Formation of G protein-coupled receptors (GPCRs) dimers and higher order oligomers represents a key mechanism in pleiotropic signaling, yet how individual protomers function within oligomers remains poorly understood. For the Class A/rhodopsin subfamily of glycoprotein hormone receptors (GpHRs), di/oligomerization has been demonstrated to play a significant role in regulating its signaling activity at a cellular...

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Identifiers

PMID: 31952685
DOI: 10.1016/bs.pmbts.2019.11.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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