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Article

Targeting of host Rab GTPase function by the intravacuolar pathogen Legionella pneumophila.

Developmental cell - 1 Jul 2006

Machner Matthias P, Isberg Ralph R

Abstract excerpt

The intracellular pathogen Legionella pneumophila replicates in a vacuole that recruits material from the host cell endoplasmic reticulum (ER). Biogenesis of this unique vacuole depends on the bacterial Dot/Icm type IV secretion system that translocates proteins across host cell membranes. Here, we show that two translocated substrates, SidM and LidA, target host cell Rab1, a small GTPase regulating ER-to-Golgi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16824952
DOI: 10.1016/j.devcel.2006.05.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Targeting of host Rab GTPase function by the intravacuolar pathogen Legionella pneumophila.PMID 16824952Read ↗

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