Article

Discovery of an autoimmunity-associated <i>IL2RA</i> enhancer by unbiased targeting of transcriptional activation

2016-12-05

Abstract excerpt

The majority of genetic variants associated with common human diseases map to enhancers, non-coding elements that shape cell type-specific transcriptional programs and responses to specific extracellular cues 1-3 . In order to understand the mechanisms by which non-coding genetic variation contributes to disease, systematic mapping of functional enhancers and their biological contexts is required. Here, we develo...

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Identifiers and source

Literature Corpus work: 01fc16d3-14bd-599c-8a26-45bdc5af3b62
DOI: 10.1101/091843

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