Article

Gene-statin interaction study identifies 9 loci that moderate statin effectiveness in blood lipids

2024-08-19

Abstract excerpt

<title>Abstract</title> <p>Hyperlipidemia, and high low-density lipoprotein cholesterol (LDL-c) in particular, is a risk factor for atherosclerosis, myocardial infarction, and stroke. High LDL-c is primarily treated with HMG-CoA reductase inhibitors, commonly known as statins. If statins interfere with the genetic pathways that endogenously increase the risk for hyperlipidemia, gene-statin interactions may identi...

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Literature Corpus work: 016ca69f-4bea-5d30-adbc-5a2b70ca1e35
DOI: 10.21203/rs.3.rs-4720582/v1

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