Article

Pharmacogenetics of HMG-CoA Reductase Inhibitors: Optimizing the Prevention of Coronary Heart Disease

2009-03-01

Abstract excerpt

The statins are the most important group of drugs for lipid-lowering therapy in the prevention of coronary heart disease. Greater reductions in LDL-cholesterol appear to be associated with greater benefits but the clinical efficacy and safety of statin treatment varies considerably from person to person because of a combination of phenotypic and genotypic factors. Pharmacogenetic studies have investigated the rela...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8af7f088-fe3a-5508-babb-021b7108debd
DOI: 10.2174/187569209787582349

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Pharmacogenetics of HMG-CoA Reductase Inhibitors: Optimizing the Prevention of Coronary Heart DiseaseDOI 10.2174/187569209787582349Read

Pharmacogenetics of HMG-CoA reductase inhibitors: exploring the potential for genotype-based individualization of coronary heart disease managementSemantic proximity Read

Pharmacogenomics of cholesterol-lowering therapy.Semantic proximity Read

Genetic determinants of response to statins.Semantic proximity Read

Genomic Variations Affecting Biological Effects of Statins.Semantic proximity Read

Impact of Pharmacogenetics on Efficacy and Safety of Statin Therapy for DyslipidemiaSemantic proximity Read

Pharmacogenetics of statins treatment: Efficacy and safetySemantic proximity Read

When the same treatment has different response: The role of pharmacogenomics in statin therapySemantic proximity Read

Clinical implications of pharmacogenetic variation on the effects of statins.Semantic proximity Read

Genetics and personalized medicine--a role in statin therapy?Semantic proximity Read

Statins personalized.Semantic proximity Read

Personalised medicine in hypercholesterolaemia: the role of pharmacogenetics in statin therapy.Semantic proximity Read

The genetic determinants of atorvastatin response.Semantic proximity Read