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Article

Genome-wide association of lipid-lowering response to statins in combined study populations.

PloS one - 22 Mar 2010

Barber Mathew J, Mangravite Lara M, Hyde Craig L, Chasman Daniel I, Smith Joshua D, McCarty Catherine A, Li Xiaohui, Wilke Russell A, Rieder Mark J, Williams Paul T, Ridker Paul M, Chatterjee Aurobindo, Rotter Jerome I, Nickerson Deborah A, Stephens Matthew, Krauss Ronald M

Abstract excerpt

BACKGROUND: Statins effectively lower total and plasma LDL-cholesterol, but the magnitude of decrease varies among individuals. To identify single nucleotide polymorphisms (SNPs) contributing to this variation, we performed a combined analysis of genome-wide association (GWA) results from three t...

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Source

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Identifiers

PMID: 20339536
DOI: 10.1371/journal.pone.0009763
PMCID: PMC2842298

Genes

CLMN
APOC1
APOE
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20339536-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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