Article
Laboratory Medicine in the Clinical Decision Support for Treatment of Hypercholesterolemia: Pharmacogenetics of Statins.
Clinics in laboratory medicine - 1 Sept 2016
Ruaño Gualberto, Seip Richard, Windemuth Andreas, Wu Alan H B, Thompson Paul D
Abstract excerpt
Statin responsiveness is an area of great research interest given the success of the drug class in the treatment of hypercholesterolemia and in primary and secondary prevention of cardiovascular disease. Interrogation of the patient's genome for gene variants will eventually guide anti-hyperlipidemic intervention. In this review, we discuss methodological approaches to discover genetic markers predictive of...
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