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Article

Common genetic variation in six lipid-related and statin-related genes, statin use and risk of incident nonfatal myocardial infarction and stroke.

Pharmacogenetics and genomics - 1 Aug 2008

Hindorff Lucia A, Lemaitre Rozenn N, Smith Nicholas L, Bis Joshua C, Marciante Kristin D, Rice Kenneth M, Lumley Thomas, Enquobahrie Daniel A, Li Guo, Heckbert Susan R, Psaty Bruce M

Abstract excerpt

OBJECTIVE: Genetic polymorphisms are associated with lipid-lowering response to statins, but generalizeability to disease endpoints is unclear. The association between 82 common single nucleotide polymorphisms (SNPs) in six lipid-related or statin-related genes (ABCB1, CETP, HMGCR, LDLR, LIPC, NOS3) and incident nonfatal myocardial infarction (MI) and ischemic stroke was analyzed according to current statin use...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18622260
DOI: 10.1097/FPC.0b013e3283033528
PMCID: PMC2736793

Genes

LIPC
CETP
LDLR
ABCB1
HMGCR
NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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