Article

GABAergic neuron-to-glioma synapses in diffuse midline gliomas

2022-11-09

Abstract excerpt

Pediatric high-grade gliomas are the leading cause of brain cancer-related death in children. High-grade gliomas include clinically and molecularly distinct subtypes that stratify by anatomical location into diffuse midline gliomas (DMG) such as diffuse intrinsic pontine glioma (DIPG) and hemispheric high-grade gliomas. Neuronal activity drives high-grade glioma progression both through paracrine signaling 1,2 an...

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Literature Corpus work: 00ed4d64-d4c2-51ba-b3ad-10c82afc9d4e
DOI: 10.1101/2022.11.08.515720

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