Article

Aperiodic neural dynamics define a novel signature of glioma-induced excitation-inhibition dysregulation

2025-05-24

Abstract excerpt

Diffuse gliomas remodel neuronal circuits with prognostic and therapeutic significance for patients. Electrophysiologic measures of cortical excitability hold promise for monitoring disease progression and evaluating therapeutic responses. The power law exponent (aperiodic slope) reflects the balance between excitatory and inhibitory activity within neuronal networks, a critical aspect of normal brain function oft...

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Literature Corpus work: f164c03a-5487-5a85-bece-8ba70da206fa
DOI: 10.1101/2025.05.23.655626

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