Article
No association of presenilin-1 intronic polymorphism and Alzheimer's disease in Australia.
Neuroscience letters - 1 May 1998
Taddei K, Yang D, Fisher C, Clarnette R, Hallmayer J, Barnetson R, Maller R, Brooks W S, Whyte S, Nicholson G A, Masters C L, Broe G A, Gandy S E, Martins R N
Abstract excerpt
We screened 703 Australian subjects for an intronic polymorphism in the presenilin-1 (PS-1) gene. PS-1 intronic allele 1 homozygosity was not associated with individuals with early- or late-onset sporadic Alzheimer's disease (EOAD or LOAD). Carriers for the PS-1 intronic allele 1 were also not associated with significantly increased risk for AD regardless of gender. Our results for the Australian population are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.