Article
No association between an intronic polymorphism in the presenilin-1 gene and Alzheimer disease in a German population.
Journal of the neurological sciences - 1 Aug 1999
Bagli M, Papassotiropoulos A, Schwab S G, Jessen F, Rao M L, Maier W, Heun R
Abstract excerpt
A polymorphism in intron 8 of the presenilin-1 (PS-1) gene has been demonstrated to increase the risk for developing late-onset Alzheimer disease (AD). Conflicting results exist for the association between this intronic polymorphism and AD probably due to variations in the PS-1 gene among different ethnic groups. We investigated the genetic association between this intronic polymorphism in the PS-1 gene and AD in...
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