Article
No association between the intronic presenilin 1 polymorphism and Alzheimer's disease in the Chinese population.
American journal of medical genetics - 5 Feb 1999
Wu X, Jiang S, Lin S, Tang G, Feng G, Qian Y, Wang D, Ren D, Gu N
Abstract excerpt
Wragg et al. [1996: Lancet 347:509-512] recorded an association between the intron-based presenilin 1 (PS1) genotype 1/1 and late-onset Alzheimer's disease (AD). This study was performed to determine if there is a similar association in the Chinese population. Ninety-one AD cases, 50 multiinfarct dementia (MID) patients, and 73 age-matched normal controls were recruited. Genotyping of PS1 and apolipoprotein E...
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